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Data extractionAll data were extracted independently by two investigators as dichotomous outcomes (presence or absence of gastric cancer). In addition pandora charms, the following clinical data were extracted for each trial: geographical location, country of origin, number of centres, method used to confirm H pylori infection, type of H pylori eradication regimen used (including dose and schedule of individual drugs within it), duration of treatment, eradication rate, duration of follow up, subsequent occurrence of oesophageal cancer, mortality from gastric cancer, mortality from other causes, and total number of adverse events reported. As some of the trials we identified performed upper gastrointestinal endoscopy and obtained gastric biopsy specimens in all recruited subjects, we were able to obtain the number of individuals in these trials with pre neoplastic lesions at baseline (defined as presence of gastric atrophy, intestinal metaplasia, or dysplasia)..

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