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The differences in choline supplementation in an animal model of schizophrenia, where rats were administered either vehicle or MK 801 (dizocilpine) injections, was investigated. This study served to replicate the findings of Gray, Gardener, Glenn (2010), who found robust affects for choline supplementation attenuating the schizophrenic symptom, anhedonia ” loss of pleasure. Periadolescent rats were put on a regular choline (1.1g/kg) or supplemental choline (5 g/kg) diet.
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